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Multiple Choice
Which organelle is primarily responsible for breaking down fatty acids via beta-oxidation, especially very-long-chain fatty acids, in eukaryotic cells?
A
Rough endoplasmic reticulum
B
Golgi apparatus
C
Nucleolus
D
Peroxisome
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Verified step by step guidance
1
Understand the function of each organelle listed: the rough endoplasmic reticulum is mainly involved in protein synthesis, the Golgi apparatus modifies and sorts proteins and lipids, and the nucleolus is responsible for ribosomal RNA synthesis.
Recall that beta-oxidation is the metabolic process of breaking down fatty acids to generate acetyl-CoA, which can then enter the citric acid cycle for energy production.
Recognize that while mitochondria perform beta-oxidation of most fatty acids, peroxisomes specialize in the breakdown of very-long-chain fatty acids that mitochondria cannot efficiently process.
Identify that peroxisomes contain enzymes specifically adapted for the initial steps of beta-oxidation of very-long-chain fatty acids, shortening them so mitochondria can further metabolize them.
Conclude that the organelle primarily responsible for breaking down very-long-chain fatty acids via beta-oxidation in eukaryotic cells is the peroxisome.