Multiple Choice
In the context of ER processing and transport, the rough endoplasmic reticulum (RER) appears “rough” because its cytosolic surface is studded with which structures?
34
views
13. Intracellular Protein Transport
ER Processing and Transport
Multiple Choice
In the context of ER processing and transport, what is the primary function of the rough endoplasmic reticulum (rough ER) in eukaryotic cells?
A
ATP production through oxidative phosphorylation and maintenance of the proton gradient
B
Synthesis of most membrane lipids and detoxification of drugs via cytochrome P450 enzymes
C
Synthesis and initial processing (folding and modification) of proteins destined for secretion, membranes, or lysosomes
D
Packaging and sorting of proteins into secretory vesicles for delivery to the plasma membrane
Verified step by step guidance1
Identify the main roles of different parts of the endoplasmic reticulum (ER) in eukaryotic cells: the rough ER and the smooth ER have distinct functions.
Recall that the rough ER is characterized by the presence of ribosomes on its cytoplasmic surface, which are responsible for protein synthesis.
Understand that the rough ER's primary function is to synthesize proteins that are destined for secretion outside the cell, incorporation into the plasma membrane, or delivery to lysosomes.
Recognize that after synthesis, these proteins undergo initial folding and post-translational modifications within the rough ER to ensure proper structure and function.
Distinguish this from the smooth ER, which is involved in lipid synthesis, detoxification, and other metabolic processes, not protein synthesis.
Related Videos
Related Practice
