Multiple Choice
In the context of translation, what is the primary function of the ribosome?
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5. DNA to RNA to Protein
Translation
Multiple Choice
In translation, the A site (aminoacyl site) of the ribosome is the location where which event occurs?
A
The growing polypeptide chain is held attached to a tRNA before transfer to the next amino acid
B
The deacylated (empty) tRNA exits the ribosome after peptide bond formation
C
An incoming aminoacyl-tRNA binds by base-pairing its anticodon with the mRNA codon
D
The small ribosomal subunit recognizes and binds the 5′ cap of eukaryotic mRNA to initiate translation
Verified step by step guidance1
Understand the structure and function of the ribosome during translation, focusing on its three key sites: the A site (aminoacyl site), the P site (peptidyl site), and the E site (exit site).
Recall that the A site is specifically where the incoming aminoacyl-tRNA binds by matching its anticodon with the codon on the mRNA, ensuring the correct amino acid is added next in the polypeptide chain.
Recognize that the growing polypeptide chain is held at the P site, where the tRNA carries the nascent polypeptide before it is transferred to the amino acid on the tRNA at the A site.
Note that the deacylated (empty) tRNA exits the ribosome from the E site after its amino acid has been added to the chain.
Understand that the small ribosomal subunit's role in recognizing and binding the 5′ cap of eukaryotic mRNA occurs during the initiation phase of translation, not at the A site.
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