Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

8. DNA Replication

Overview of DNA Replication

Genetics

8. DNA Replication

Overview of DNA Replication

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Multiple Choice

Which of the following best describes the product of DNA replication?

A single double-stranded DNA molecule with random mutations

Two identical double-stranded DNA molecules

Four non-identical DNA strands

One single-stranded RNA molecule

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Verified step by step guidance

Understand the process of DNA replication: it is a biological mechanism where a double-stranded DNA molecule is copied to produce two identical double-stranded DNA molecules.

Recall that DNA replication is semi-conservative, meaning each new DNA molecule consists of one original (parental) strand and one newly synthesized strand.

Recognize that the product of DNA replication is not a single molecule with mutations, but rather two molecules that are identical to the original DNA molecule, barring any rare replication errors.

Eliminate options that describe RNA molecules or non-identical strands, since DNA replication specifically produces DNA, not RNA, and the strands produced are complementary and identical in sequence to the original.

Conclude that the best description of the product of DNA replication is two identical double-stranded DNA molecules.

5:02m

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Textbook Question

Suppose that future exploration of polar ice on Mars identifies a living microbe and that analysis indicates the organism carries double-stranded DNA as its genetic material. Suppose further that DNA replication analysis is performed by first growing the microbe in a growth medium containing the heavy isotope of nitrogen (¹⁴N) that the organism is then transferred to a growth medium containing the light isotope of nitrogen (¹⁴N) and that the nitrogen composition of the DNA is examined by CsCl ultracentrifugation and densitometry after the first, second, and third replication cycles in the ¹⁴N-containing medium. The results of the experiment are illustrated here for each cycle. The control shows the positioning of the three possible DNA densities. Based on the results shown, what can you conclude about the mechanism of DNA replication in this organism?

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