Cattle breeders would like to improve the protein content and butterfat content of milk produced by a herd of cows. Narrow sense heritability values are 0.60 for protein content and 0.80 for butterfat content. The average percentages of these traits in the herd and the percentages of the traits in cows selected for breeding are as follows. Trait Herd Average Selected Cows Protein content 20.2% 22.7% Butterfat content 6.5% 7.4% Which trait is likely to be the most responsive to artificial selection applied by the cattle breeders through selection of cows for mating?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
Problem 26a
Textbook Question
The children of couples in which one partner has blood type O (genotype ii) and the other partner has blood type AB (genotype IᴬIᴮ) are studied. What is the expected concordance rate for blood type of MZ twins in this study? Explain your answer.

1
Determine the possible genotypes of the offspring by performing a Punnett square for the cross between one parent with genotype ii (blood type O) and the other parent with genotype IᴬIᴮ (blood type AB).
Set up the Punnett square: Place the alleles from the ii parent (i, i) on one side and the alleles from the IᴬIᴮ parent (Iᴬ, Iᴮ) on the other side. Fill in the grid to determine the offspring genotypes.
Analyze the results of the Punnett square. The possible genotypes of the offspring will be Iᴬi and Iᴮi, corresponding to blood types A and B, respectively. Note that no offspring will have blood type O or AB in this cross.
Understand the concept of concordance rate in monozygotic (MZ) twins. MZ twins are genetically identical, so they will always have the same genotype and, therefore, the same blood type. This means the concordance rate for blood type in MZ twins is 100%.
Conclude that since MZ twins share identical genotypes, the expected concordance rate for blood type in this study is 100%, regardless of whether the offspring have blood type A (Iᴬi) or blood type B (Iᴮi).

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Blood Type Inheritance
Blood type is determined by the ABO gene, which has three alleles: A (Iᴬ), B (Iᴮ), and O (i). Individuals with blood type O have the genotype ii, while those with blood type AB have the genotype IᴬIᴮ. The offspring of these parents can inherit one allele from each parent, leading to potential blood types A (Iᴬi) or B (Iᴮi), but not O or AB.
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Monozygotic (MZ) Twins
Monozygotic twins, or identical twins, arise from a single fertilized egg that splits into two embryos. They share 100% of their genetic material, which means that any genetic traits, including blood type, will be concordant. In this context, the study of MZ twins helps to understand the genetic basis of blood type inheritance.
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Concordance Rate
Concordance rate refers to the probability that both twins in a pair exhibit the same trait or condition. In the case of MZ twins, the concordance rate for blood type would be expected to be high, as they share identical genetic information. Given the blood types possible from the parents, the expected concordance rate for MZ twins in this study would be 100% for the blood types A and B.
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