The children of couples in which one partner has blood type O (genotype ii) and the other partner has blood type AB (genotype IᴬIᴮ) are studied. What is the expected concordance rate for blood type of MZ twins in this study? Explain your answer.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
Problem 28b
Textbook Question
Floral traits in plants often play key roles in diversification, in that slight modifications of those traits, if genetically determined, may quickly lead to reproductive restrictions and evolution. Insight into genetic involvement in flower formation is often acquired through selection experiments that expose realized heritability. Lendvai and Levin (2003) conducted a series of artificial selection experiments on flower size (diameter) in Phlox drummondii. Data from their selection experiments are presented in the following table in modified form and content.

Calculate the realized heritability for each year and the overall realized heritability.

1
Step 1: Understand the concept of realized heritability. Realized heritability (h^2) is calculated using the formula: h^2 = R / S, where R is the response to selection (difference between offspring mean and control mean) and S is the selection differential (difference between selected parents mean and control mean).
Step 2: For each year, calculate the selection differential (S). Use the formula S = Mean of selected parents - Mean of control. For example, for 1997, S = 34.13 - 30.04.
Step 3: For each year, calculate the response to selection (R). Use the formula R = Mean of offspring - Mean of control. For example, for 1997, R = 32.21 - 30.04.
Step 4: Calculate the realized heritability (h^2) for each year using the formula h^2 = R / S. Perform this calculation for 1997, 1998, and 1999 using the values of R and S obtained in the previous steps.
Step 5: To find the overall realized heritability, average the h^2 values calculated for each year. This provides a single value representing the overall heritability across all years.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Realized Heritability
Realized heritability is a measure of the proportion of phenotypic variance in a trait that can be attributed to genetic variance, as observed in a specific population under certain environmental conditions. It is calculated using selection experiments, where the response to selection is compared to the initial phenotypic variance. This concept is crucial for understanding how traits can evolve over generations through natural or artificial selection.
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Artificial Selection
Artificial selection is a process in which humans intentionally breed plants or animals for specific traits, such as flower size in Phlox drummondii. This method allows researchers to observe the effects of selective pressure on trait variation and can provide insights into the genetic basis of those traits. By manipulating breeding, scientists can study how traits are inherited and how quickly they can change in a population.
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Phenotypic Variation
Phenotypic variation refers to the observable differences in traits among individuals in a population, which can be influenced by both genetic and environmental factors. In the context of the question, flower size is a trait that exhibits phenotypic variation, and understanding this variation is essential for calculating realized heritability. It highlights the importance of measuring traits accurately to assess their genetic basis and evolutionary potential.
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