Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

6. Chromosomal Variation

Chromosomal Rearrangements: Translocations

Genetics

6. Chromosomal Variation

Chromosomal Rearrangements: Translocations

Previous problemNext problem

3: minutes

Problem 7g

Textbook Question

From the following list, identify the types of chromosome changes you expect to show phenotypic consequences.
Paracentric inversion

Verified step by step guidance

Understand the concept of a paracentric inversion: A paracentric inversion is a type of chromosomal rearrangement where a segment of a chromosome is flipped in orientation, but this inversion does not include the centromere.

Recall that paracentric inversions can lead to phenotypic consequences due to the disruption of gene sequences or regulatory regions within the inverted segment. This can affect gene expression or function.

Consider the effects during meiosis: Paracentric inversions can lead to the formation of inversion loops during homologous chromosome pairing. Crossing over within the inversion loop can produce gametes with duplications and deletions, which may result in phenotypic abnormalities in offspring.

Evaluate whether the inversion disrupts any essential genes or regulatory elements. If the inversion breaks a gene or alters its regulatory region, it can directly lead to phenotypic consequences.

Conclude that paracentric inversions can show phenotypic consequences depending on the specific genes or regions affected by the inversion and the genetic outcomes during meiosis.

Verified video answer for a similar problem:

This video solution was recommended by our tutors as helpful for the problem above

Video duration:

Play a video:

Was this helpful?

Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Chromosome Structure

Chromosomes are structures within cells that contain DNA and proteins. They are essential for the proper segregation of genetic material during cell division. Changes in chromosome structure, such as inversions, can disrupt gene function and lead to phenotypic consequences, affecting traits and characteristics of an organism.

Paracentric Inversion

A paracentric inversion is a type of chromosomal rearrangement where a segment of a chromosome is inverted, but does not include the centromere. This alteration can lead to the formation of abnormal gametes during meiosis, potentially resulting in offspring with genetic abnormalities or altered phenotypes due to disrupted gene sequences.

Phenotypic Consequences

Phenotypic consequences refer to the observable traits or characteristics of an organism that result from its genetic makeup and environmental influences. Changes in chromosome structure, such as those caused by paracentric inversions, can lead to variations in phenotype, which may manifest as physical, biochemical, or behavioral differences in the organism.

Watch next

Master Reciprocal Translocation with a bite sized video explanation from Kylia

Start learning

Related Videos

Related Practice

Textbook Question

A boy with Down syndrome (trisomy 21) has 46 chromosomes. His parents and his two older sisters have a normal phenotype, but each has 45 chromosomes.

Explain how this is possible.

362

views

Textbook Question

A woman who sought genetic counseling is found to be heterozygous for a chromosomal rearrangement between the second and third chromosomes. Her chromosomes, compared to those in a normal karyotype, are diagrammed to the right. This woman is phenotypically normal. Does this surprise you? Why or why not? Under what circumstances might you expect a phenotypic effect of such a rearrangement?

A normal chromosome and its homolog carrying a paracentric inversion are shown here. The dot (·) represents the centromere.

Normal ABC • DEFGHIJK

Inversion abc • djihgfe

Diagram the alignment of chromosomes during prophase I.

370

views

Multiple Choice

Which type of chromosomal rearrangement occurs when part of a chromosome breaks off and attaches to a nonhomologous chromosome?

views

Multiple Choice

Which of the following represents the chromosomal segregation into gametes after a reciprocal translocation caused by adjacent-1 segregation? N=Normal chromosome T = Tanslocated chromosome

Which of the following ways reciprocal translocated chromosomes are sorted produces viable gametes?

An individual heterozygous for a reciprocal translocation has the following chromosomes. Which chromosomes do the gametes receive after alternative segregation?

A B • C D E F G J K • L M N O P

A B • C D N O P J K • L M E F G