Multiple Choice
Which of the following outlines the overall pathway of glycerol metabolism?
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24. Lipid Metabolism
Glycerol Metabolism
Multiple Choice
The glycerol derived from lipolysis of a triglyceride molecule is converted into glycerol-3-phosphate followed by dihydroxyacetone phosphate. Which step does this dihydroxyacetone phosphate enter in terms of glycolysis?
A
Step 1
B
Step 3
C
Step 5
D
Step 10
Verified step by step guidance1
Understand that glycerol derived from triglycerides is first converted to glycerol-3-phosphate by the enzyme glycerol kinase.
Glycerol-3-phosphate is then oxidized to dihydroxyacetone phosphate (DHAP) by the enzyme glycerol-3-phosphate dehydrogenase.
Recognize that dihydroxyacetone phosphate is an intermediate in the glycolysis pathway.
Recall that in glycolysis, dihydroxyacetone phosphate is isomerized to glyceraldehyde-3-phosphate by the enzyme triose phosphate isomerase.
Identify that the conversion of dihydroxyacetone phosphate to glyceraldehyde-3-phosphate occurs at Step 5 of glycolysis, where both molecules are involved in the pathway.
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