Textbook Question
Name the metabolic substrate(s) that can be produced from the carbon atoms of each of the following amino acids:
a. alanine
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25. Protein and Amino Acid Metabolism
Amino Acid Catabolism: Carbon Atoms
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Identify amino acid that is considered to be glucogenic but not ketogenic.
A
Phenylalanine
B
Leucine
C
Tyrosine
D
Aspartate
E
Lysine
Verified step by step guidance1
Understand the definitions: Glucogenic amino acids are those that can be converted into glucose through gluconeogenesis. Ketogenic amino acids are those that can be converted into ketone bodies.
Identify the amino acids listed: Phenylalanine, Leucine, Tyrosine, Aspartate, and Lysine.
Recall that glucogenic amino acids are those that can be converted into intermediates of the citric acid cycle or pyruvate, which can then be used to produce glucose.
Recognize that Aspartate is an amino acid that can be converted into oxaloacetate, an intermediate of the citric acid cycle, making it glucogenic.
Note that Leucine and Lysine are exclusively ketogenic, while Phenylalanine and Tyrosine are both glucogenic and ketogenic. Therefore, Aspartate is the amino acid that is glucogenic but not ketogenic.
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