Textbook Question
From what two amino acids do the nitrogens in urea arise?
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25. Protein and Amino Acid Metabolism
The Urea Cycle
Multiple Choice
What is the function of aspartate in the urea cycle?
A
Produces CO2 for carbamoyl phosphate synthesis.
B
Provides –NH2 group as ammonium ion.
C
Produces succinate for citrulline formation.
D
Provides the second nitrogen atom for urea.
Verified step by step guidance1
Understand the urea cycle: The urea cycle is a series of biochemical reactions that produce urea from ammonia. It is a crucial process for removing excess nitrogen from the body.
Identify the role of aspartate: In the urea cycle, aspartate provides the second nitrogen atom needed for the synthesis of urea.
Examine the reaction involving aspartate: Aspartate combines with citrulline to form argininosuccinate, which is then converted to arginine, releasing fumarate.
Recognize the importance of nitrogen atoms: Urea contains two nitrogen atoms, one from ammonia and the other from aspartate, highlighting the importance of aspartate in the cycle.
Connect the function of aspartate to the overall cycle: By providing the second nitrogen atom, aspartate plays a critical role in the conversion of toxic ammonia into urea, which can be safely excreted from the body.
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