Table of contents

Skip topic navigation

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

16. The Endocrine System

Membrane Bound Receptors and Secondary Messengers

Anatomy & Physiology

16. The Endocrine System

Membrane Bound Receptors and Secondary Messengers

Previous problemNext problem

Struggling with Anatomy & Physiology?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Which second messenger remains in the membrane after the cleavage of PIP2?

Diacylglycerol (DAG)

Cyclic AMP (cAMP)

Inositol trisphosphate (IP3)

Calcium ions (Ca2+)

Previous problemNext problem

Verified step by step guidance

Understand the context: PIP2 (phosphatidylinositol 4,5-bisphosphate) is a phospholipid found in the cell membrane that can be cleaved by the enzyme phospholipase C.

Identify the products of PIP2 cleavage: When PIP2 is cleaved by phospholipase C, it produces two second messengers: inositol trisphosphate (IP3) and diacylglycerol (DAG).

Determine the location of each product: IP3 is soluble and diffuses into the cytoplasm, where it can release calcium ions from the endoplasmic reticulum.

Recognize the role of DAG: Diacylglycerol (DAG) remains in the membrane because it is hydrophobic and acts as a second messenger by activating protein kinase C (PKC).

Conclude which second messenger remains in the membrane: Based on the above steps, DAG is the second messenger that remains in the membrane after the cleavage of PIP2.