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Multiple Choice
Which of the following statements regarding MHC II proteins is true?
A
MHC II proteins are primarily expressed on antigen-presenting cells.
B
MHC II proteins are involved in the presentation of endogenous antigens.
C
MHC II proteins are found on all nucleated cells.
D
MHC II proteins present antigens to CD8+ T cells.
Verified step by step guidance
1
Understand the role of MHC II proteins: MHC II proteins are crucial for the immune response, specifically in presenting antigens to certain immune cells.
Identify the types of cells that express MHC II proteins: MHC II proteins are primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells.
Differentiate between MHC I and MHC II proteins: MHC I proteins are found on all nucleated cells and present endogenous antigens to CD8+ T cells, while MHC II proteins present exogenous antigens to CD4+ T cells.
Clarify the type of antigens presented by MHC II: MHC II proteins present exogenous antigens, which are typically derived from extracellular pathogens that have been engulfed and processed by APCs.
Determine the correct statement: Based on the understanding of MHC II proteins, the true statement is that they are primarily expressed on antigen-presenting cells.