Multiple Choice
In which part of the gastrointestinal tract is the enzyme pepsin active?
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How does each of the three phases of gastric secretion promote and facilitate gastric control?
Describe the regulation of the cephalic, gastric, and intestinal phases of gastric secretion.
Proton Pump Inhibitors (or PPIs) are some of the widely used drugs in the world and are prescribed for chronic heartburn/acid reflux. They work by inhibiting the movement of H+ ions across the membrane into the gastric juice, thereby lowering the concentration of HCl. As described, which cell of the gastric glands would you expect PPIs to affect?