22. The Respiratory System

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Oxygen is transported primarily by dissolving in the plasma.

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Each Hb protein can carry up to four oxygen molecules.

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Hb in arterial blood is normally almost fully saturated.

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When the PO₂ of arterial blood drops slightly, the percent saturation of Hb drops dramatically.

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Increased P_CO2, temperature, and hydrogen ion concentration all increase Hb's affinity for oxygen.