Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism

Pyruvate Oxidation

Biochemistry

Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism

Pyruvate Oxidation

Previous problem

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Multiple Choice

Which process occurs after glycolysis but before the citric acid cycle in cellular respiration?

Conversion of glucose to pyruvate

Electron transport chain

Substrate-level phosphorylation in the cytosol

Oxidative decarboxylation of pyruvate to acetyl-CoA

Previous problem

Verified step by step guidance

Understand that glycolysis is the first step in cellular respiration, where glucose is converted into pyruvate in the cytosol.

Recognize that the citric acid cycle (also known as the Krebs cycle) occurs in the mitochondrial matrix and requires acetyl-CoA as its starting substrate.

Learn that before the citric acid cycle can begin, pyruvate produced during glycolysis must be transported into the mitochondria.

Identify the process of oxidative decarboxylation, where pyruvate is converted into acetyl-CoA by the enzyme pyruvate dehydrogenase complex. This reaction involves the removal of a carboxyl group from pyruvate, releasing CO₂, and the transfer of electrons to NAD⁺ to form NADH.

Understand that the acetyl-CoA produced in this step is then used as the substrate for the citric acid cycle, linking glycolysis to the citric acid cycle in cellular respiration.