Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism

Pyruvate Oxidation

Biochemistry

Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism

Pyruvate Oxidation

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Multiple Choice

Which of the following are produced when pyruvate is oxidized to acetyl-CoA during cellular respiration?

NADH, CO$_2$, and acetyl-CoA

ATP, FADH$_2$, and lactate

NADPH, O$_2$, and citrate

GTP, CO$_2$, and oxaloacetate

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Verified step by step guidance

Understand the context: Pyruvate oxidation is a key step in cellular respiration that occurs in the mitochondrial matrix. It links glycolysis to the citric acid cycle (Krebs cycle). During this process, pyruvate is converted into acetyl-CoA by the enzyme pyruvate dehydrogenase complex.

Identify the reactants and products: Pyruvate (a 3-carbon molecule) is oxidized, resulting in the production of acetyl-CoA (a 2-carbon molecule attached to coenzyme A), carbon dioxide (CO$_2$), and NADH (reduced nicotinamide adenine dinucleotide).

Recall the role of NADH: During pyruvate oxidation, one molecule of NAD$^+$ is reduced to NADH. This is an important step as NADH will later donate electrons to the electron transport chain to produce ATP.

Understand the release of CO$_2$: One carbon atom from pyruvate is released as CO$_2$ during the decarboxylation step, reducing the 3-carbon pyruvate to a 2-carbon acetyl group.

Eliminate incorrect options: ATP, FADH$_2$, lactate, NADPH, O$_2$, citrate, GTP, and oxaloacetate are not products of pyruvate oxidation. The correct answer includes NADH, CO$_2$, and acetyl-CoA.