Multiple Choice
In cellular respiration, which pathway produces the greatest amount of ATP per molecule of glucose under typical conditions in eukaryotic cells?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In cellular respiration, which stage produces the greatest amount of ATP per glucose molecule?
A
Citric acid cycle (Krebs cycle)
B
Oxidative phosphorylation (electron transport chain and chemiosmosis)
C
Pyruvate oxidation (conversion of pyruvate to acetyl-CoA)
D
Glycolysis
Verified step by step guidance1
Identify the main stages of cellular respiration: Glycolysis, Pyruvate Oxidation, Citric Acid Cycle (Krebs cycle), and Oxidative Phosphorylation (Electron Transport Chain and Chemiosmosis).
Understand the ATP yield from each stage: Glycolysis produces a small amount of ATP directly, Pyruvate Oxidation does not produce ATP directly, the Citric Acid Cycle produces some ATP (or GTP) directly, and Oxidative Phosphorylation produces ATP indirectly through the electron transport chain and chemiosmosis.
Recall that during Oxidative Phosphorylation, electrons from NADH and FADH2 are transferred through protein complexes in the mitochondrial membrane, creating a proton gradient.
Recognize that the proton gradient drives ATP synthase to produce ATP from ADP and inorganic phosphate, resulting in the largest ATP yield per glucose molecule compared to other stages.
Conclude that Oxidative Phosphorylation is the stage that produces the greatest amount of ATP per glucose molecule because it harnesses the energy stored in electron carriers generated in previous stages.
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