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Multiple Choice
In aerobic cellular respiration, which stage produces the most ATP per glucose molecule under typical conditions in eukaryotic cells?
A
Glycolysis
B
Citric acid cycle (Krebs cycle)
C
Pyruvate oxidation (conversion of pyruvate to acetyl-CoA)
D
Oxidative phosphorylation (electron transport chain and ATP synthase via chemiosmosis)
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Verified step by step guidance
1
Understand the overall process of aerobic cellular respiration, which includes glycolysis, pyruvate oxidation, the citric acid cycle, and oxidative phosphorylation.
Recall that glycolysis produces a small amount of ATP directly by substrate-level phosphorylation and generates NADH for later use.
Recognize that pyruvate oxidation itself does not produce ATP directly but generates NADH, which feeds into the electron transport chain.
Know that the citric acid cycle produces some ATP (or GTP) directly and also generates NADH and FADH2, which carry electrons to the electron transport chain.
Identify that oxidative phosphorylation, which includes the electron transport chain and ATP synthase activity via chemiosmosis, produces the majority of ATP by using the energy from NADH and FADH2 to drive ATP synthesis.