Multiple Choice
In cellular respiration, which stage produces the greatest amount of ATP per glucose molecule?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In oxidative phosphorylation, what is the primary role of NADH in cellular respiration?
A
It serves as the final electron acceptor, combining with electrons and protons to form water.
B
It transports oxygen from the lungs to tissues to support aerobic metabolism.
C
It directly catalyzes the phosphorylation of ADP to ATP at ATP synthase.
D
It donates high-energy electrons to Complex I of the electron transport chain, helping drive proton pumping across the inner mitochondrial membrane.
Verified step by step guidance1
Understand the role of NADH in cellular respiration, specifically in the context of oxidative phosphorylation.
Recall that NADH is a reduced coenzyme that carries high-energy electrons derived from metabolic pathways like glycolysis and the citric acid cycle.
Recognize that NADH donates these high-energy electrons to Complex I (NADH dehydrogenase) of the electron transport chain located in the inner mitochondrial membrane.
Know that the transfer of electrons from NADH through Complex I initiates a series of redox reactions that pump protons (H\+ ions) from the mitochondrial matrix to the intermembrane space, creating a proton gradient.
This proton gradient then drives ATP synthesis by ATP synthase, but NADH itself does not directly catalyze ATP formation or act as the final electron acceptor.
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