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Multiple Choice
Which of the following statements is NOT true regarding lipid metabolism?
A
Fatty acid synthesis primarily takes place in the cytoplasm.
B
Chylomicrons are responsible for transporting lipids from the liver to peripheral tissues.
C
Beta-oxidation of fatty acids occurs in the mitochondria.
D
Ketone bodies are synthesized in the liver during prolonged fasting.
Verified step by step guidance
1
Step 1: Understand the context of lipid metabolism. Lipid metabolism involves the synthesis, breakdown, and transport of lipids in the body. Key processes include fatty acid synthesis, beta-oxidation, ketone body synthesis, and lipid transport.
Step 2: Analyze the first statement: 'Fatty acid synthesis primarily takes place in the cytoplasm.' This is true because fatty acid synthesis occurs in the cytoplasm of cells, particularly in the liver and adipose tissue, using acetyl-CoA as a precursor.
Step 3: Analyze the second statement: 'Chylomicrons are responsible for transporting lipids from the liver to peripheral tissues.' This is NOT true. Chylomicrons are responsible for transporting dietary lipids from the intestines to peripheral tissues, not from the liver. Lipids from the liver are transported by very-low-density lipoproteins (VLDLs).
Step 4: Analyze the third statement: 'Beta-oxidation of fatty acids occurs in the mitochondria.' This is true because beta-oxidation, the process of breaking down fatty acids to generate acetyl-CoA, occurs in the mitochondrial matrix.
Step 5: Analyze the fourth statement: 'Ketone bodies are synthesized in the liver during prolonged fasting.' This is true because during prolonged fasting, the liver converts acetyl-CoA into ketone bodies, which serve as an alternative energy source for peripheral tissues, including the brain.