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Multiple Choice
In oxidative phosphorylation, what is the primary role of ATP synthase in the inner mitochondrial membrane?
A
To use the proton-motive force to catalyze the synthesis of ATP from ADP and inorganic phosphate (Pi)
B
To transfer electrons from NADH to ubiquinone (coenzyme Q)
C
To pump protons from the intermembrane space back into the mitochondrial matrix to build the proton gradient
D
To hydrolyze ATP to drive the transport of electrons through the electron transport chain
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Verified step by step guidance
1
Understand the context of oxidative phosphorylation, which occurs in the inner mitochondrial membrane and involves the electron transport chain and ATP synthesis.
Recognize that ATP synthase is an enzyme complex embedded in the inner mitochondrial membrane responsible for producing ATP.
Recall that the electron transport chain creates a proton gradient (proton-motive force) by pumping protons from the mitochondrial matrix to the intermembrane space.
Identify that ATP synthase uses the energy stored in this proton gradient to catalyze the formation of ATP from ADP and inorganic phosphate (Pi) as protons flow back into the matrix.
Distinguish ATP synthase's role from other components: it does not transfer electrons or pump protons but harnesses the proton gradient to synthesize ATP.