Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

Which of the following correctly represents the mechanism of enzyme function?

The enzyme reacts with the product to regenerate the substrate.

The enzyme permanently binds to the substrate and is consumed in the reaction.

The enzyme increases the activation energy required for the reaction to proceed.

The enzyme binds to the substrate to form an enzyme-substrate complex, lowers the activation energy, and releases the product.

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Verified step by step guidance

Understand the role of enzymes in biochemical reactions: Enzymes are biological catalysts that speed up reactions by lowering the activation energy required for the reaction to proceed.

Clarify the concept of the enzyme-substrate complex: Enzymes bind specifically to their substrate at the active site, forming an enzyme-substrate complex. This is a temporary interaction that facilitates the reaction.

Explain the lowering of activation energy: The enzyme stabilizes the transition state of the reaction, reducing the energy barrier and allowing the reaction to occur more efficiently.

Describe the release of the product: After the reaction occurs, the enzyme releases the product and remains unchanged, ready to catalyze another reaction cycle.

Highlight the correct mechanism: The enzyme does not react with the product to regenerate the substrate, nor is it consumed in the reaction. Instead, it binds to the substrate, lowers the activation energy, and releases the product without being permanently altered.