Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

Why is the induced fit of an enzyme important as it binds its substrate?

It increases the activation energy required for the reaction.

It prevents the substrate from binding to the enzyme.

It causes the enzyme to become permanently inactivated after substrate binding.

It allows the enzyme to undergo a conformational change that optimally positions catalytic residues for the reaction.

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Verified step by step guidance

Understand the concept of induced fit: Induced fit refers to the dynamic process where an enzyme undergoes a conformational change upon substrate binding. This change optimally positions the enzyme's active site for catalysis.

Recognize the role of catalytic residues: Enzymes have specific amino acid residues in their active site that participate in the chemical reaction. The induced fit ensures these residues are properly aligned to interact with the substrate.

Analyze the importance of conformational change: The conformational change reduces the energy barrier for the reaction by stabilizing the transition state, thereby lowering the activation energy required for the reaction.

Eliminate incorrect options: Review the provided choices and discard options that contradict the function of induced fit, such as increasing activation energy or permanently inactivating the enzyme.

Conclude the correct answer: The induced fit mechanism allows the enzyme to undergo a conformational change that optimally positions catalytic residues for the reaction, ensuring efficient catalysis.