Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

Which of the following statements best explains how the enzyme speeds up the reaction involving the enzyme-substrate complex?

The enzyme lowers the activation energy required for the reaction to proceed.

The enzyme alters the equilibrium constant of the reaction.

The enzyme increases the overall free energy change (9G) of the reaction.

The enzyme permanently binds to the substrate, preventing product formation.

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Verified step by step guidance

Understand the role of enzymes in biochemical reactions: Enzymes are biological catalysts that speed up reactions by lowering the activation energy required for the reaction to proceed. They do not alter the equilibrium constant or the overall free energy change (ΔG) of the reaction.

Analyze the options provided: Evaluate each statement to determine its accuracy based on enzyme function. For example, enzymes do not permanently bind to substrates; they form temporary enzyme-substrate complexes and release products after the reaction.

Focus on activation energy: Recall that enzymes work by stabilizing the transition state of the reaction, which reduces the energy barrier (activation energy) needed for the reaction to occur.

Eliminate incorrect options: The equilibrium constant of a reaction is determined by the ratio of product to reactant concentrations at equilibrium and is not altered by enzymes. Similarly, enzymes do not increase the overall free energy change (ΔG) of the reaction, as ΔG is a thermodynamic property of the reaction itself.

Select the correct explanation: Based on the analysis, the correct statement is that the enzyme lowers the activation energy required for the reaction to proceed, which is the fundamental mechanism by which enzymes speed up reactions.