Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

What is meant by the "induced fit" of an enzyme?

The enzyme changes its shape slightly to better fit the substrate upon binding.

The enzyme and substrate bind without any change in their shapes, like a lock and key.

The enzyme permanently alters its structure after binding to the substrate.

The substrate is forced to change its shape to fit the rigid active site of the enzyme.

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Verified step by step guidance

Understand the concept of enzyme-substrate interaction: Enzymes are biological catalysts that speed up chemical reactions by lowering the activation energy. They achieve this by binding to specific substrates at their active sites.

Learn about the 'induced fit' model: Unlike the 'lock and key' model, which suggests a perfect fit between enzyme and substrate, the 'induced fit' model proposes that the enzyme's active site undergoes a slight conformational change upon substrate binding to better accommodate the substrate.

Clarify the mechanism: When the substrate approaches the enzyme, interactions between the substrate and the enzyme's active site cause the enzyme to adjust its shape. This adjustment enhances the binding and positions the substrate optimally for the reaction to occur.

Differentiate from other options: The enzyme does not permanently alter its structure after binding, nor does the substrate change its shape to fit a rigid active site. These descriptions are inconsistent with the induced fit model.

Summarize the induced fit model: The induced fit model emphasizes the dynamic nature of enzyme-substrate interactions, where the enzyme adapts its shape slightly to ensure a precise fit and efficient catalysis.