Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzymes

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzymes

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Multiple Choice

Which enzyme is responsible for unwinding and opening the DNA double helix during DNA replication?

Helicase

DNA polymerase

Topoisomerase

Ligase

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Verified step by step guidance

Understand the context: DNA replication is the process by which a cell duplicates its DNA before cell division. During this process, the double-stranded DNA must be unwound to allow the replication machinery to access the template strands.

Identify the role of each enzyme listed: Helicase, DNA polymerase, Topoisomerase, and Ligase. Each has a specific function in DNA replication.

Focus on Helicase: Helicase is the enzyme responsible for breaking the hydrogen bonds between the complementary base pairs of the DNA strands, effectively unwinding and opening the double helix.

Clarify the roles of the other enzymes: DNA polymerase synthesizes the new DNA strand by adding nucleotides to the template strand. Topoisomerase relieves the supercoiling tension caused by the unwinding of DNA. Ligase seals the nicks in the sugar-phosphate backbone of the DNA, joining Okazaki fragments on the lagging strand.

Conclude that Helicase is the enzyme directly responsible for unwinding and opening the DNA double helix during DNA replication.