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Multiple Choice
Most drugs that inhibit protein synthesis or translation block the action of the:
A
DNA polymerase
B
ribosome
C
RNA polymerase
D
proteasome
Verified step by step guidance
1
Understand the process of protein synthesis: Protein synthesis involves transcription (DNA to RNA) and translation (RNA to protein). Translation occurs in the ribosome, where mRNA is decoded to synthesize proteins.
Identify the role of each component mentioned in the problem: DNA polymerase is involved in DNA replication, RNA polymerase is responsible for transcription, and the proteasome is involved in protein degradation, not synthesis.
Focus on the ribosome: The ribosome is the cellular machinery responsible for translation, where mRNA is read and amino acids are assembled into a polypeptide chain.
Recognize that drugs targeting protein synthesis typically interfere with ribosomal function: These drugs may block ribosomal subunits, inhibit tRNA binding, or disrupt peptide bond formation, all of which are critical for translation.
Conclude that the ribosome is the correct answer: Since the ribosome is directly involved in translation, drugs that inhibit protein synthesis or translation would target the ribosome.