Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Biochemistry

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Previous problemNext problem

Struggling with Biochemistry?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Assuming the same isoenzyme concentration, which type of enzyme inhibition can be overcome by increasing the substrate concentration?

Noncompetitive inhibition

Competitive inhibition

Uncompetitive inhibition

Irreversible inhibition

Previous problemNext problem

Verified step by step guidance

Understand the concept of enzyme inhibition: Enzyme inhibitors are molecules that reduce the activity of enzymes. Different types of inhibition affect the enzyme's ability to bind to the substrate or catalyze the reaction in distinct ways.

Review competitive inhibition: In competitive inhibition, the inhibitor competes with the substrate for binding to the active site of the enzyme. Increasing the substrate concentration can outcompete the inhibitor, allowing the enzyme to function normally.

Contrast competitive inhibition with noncompetitive inhibition: In noncompetitive inhibition, the inhibitor binds to a site other than the active site, altering the enzyme's structure and reducing its activity. This type of inhibition cannot be overcome by increasing substrate concentration.

Examine uncompetitive inhibition: In uncompetitive inhibition, the inhibitor binds only to the enzyme-substrate complex, preventing the reaction from proceeding. Increasing substrate concentration does not overcome this type of inhibition.

Consider irreversible inhibition: Irreversible inhibitors permanently bind to or modify the enzyme, rendering it inactive. This type of inhibition cannot be reversed by increasing substrate concentration.