Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Peptide Bond

Biochemistry

4. Protein Structure

Peptide Bond

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Multiple Choice

Which of the following statements concerning peptide bond formation is correct?

Peptide bond formation requires the direct addition of water to the reacting amino acids.

Peptide bond formation is a spontaneous process that does not require energy in biological systems.

Peptide bonds are formed between the side chains (R groups) of amino acids.

A peptide bond is formed by a condensation reaction between the amino group of one amino acid and the carboxyl group of another.

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Verified step by step guidance

Understand the concept of peptide bond formation: A peptide bond is a covalent bond formed between two amino acids during protein synthesis. It involves the amino group (-NH₂) of one amino acid and the carboxyl group (-COOH) of another amino acid.

Recognize the type of reaction involved: Peptide bond formation occurs through a condensation reaction, also known as a dehydration synthesis. This means that a molecule of water (H₂O) is removed during the bond formation.

Clarify the energy requirement: In biological systems, peptide bond formation is not spontaneous and requires energy. This energy is typically provided by ATP during protein synthesis in ribosomes.

Identify the correct bonding sites: Peptide bonds are formed between the amino group of one amino acid and the carboxyl group of another amino acid, not between the side chains (R groups). The R groups remain free and contribute to the protein's structure and function.

Summarize the correct statement: The correct answer is that a peptide bond is formed by a condensation reaction between the amino group of one amino acid and the carboxyl group of another, with the removal of water.