Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Biochemistry

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

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Multiple Choice

Which of the following types of enzyme inhibitors primarily target protein conformation?

Uncompetitive inhibitors

Allosteric activators

Competitive inhibitors

Noncompetitive inhibitors

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Verified step by step guidance

Understand the concept of enzyme inhibition: Enzyme inhibitors are molecules that reduce or prevent the activity of enzymes. They can act by binding to the enzyme and altering its function or structure.

Review the mechanism of noncompetitive inhibitors: Noncompetitive inhibitors bind to a site other than the active site of the enzyme. This binding causes a conformational change in the enzyme, which reduces its ability to catalyze the reaction effectively.

Compare noncompetitive inhibitors with other types: Competitive inhibitors bind directly to the active site, preventing substrate binding. Uncompetitive inhibitors bind only to the enzyme-substrate complex, stabilizing it and reducing enzyme activity. Allosteric activators enhance enzyme activity by binding to allosteric sites, but they are not inhibitors.

Focus on protein conformation: Noncompetitive inhibitors primarily target protein conformation by inducing structural changes in the enzyme, which affects its catalytic activity without competing with the substrate for the active site.

Conclude that noncompetitive inhibitors are the correct answer: Based on the mechanism of action, noncompetitive inhibitors are the type of enzyme inhibitors that primarily target protein conformation.