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Multiple Choice
During which phase of mitosis do sister chromatids separate?
A
Metaphase
B
Prophase
C
Telophase
D
Anaphase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during metaphase, the chromosomes align at the cell's equatorial plane, known as the metaphase plate. The sister chromatids are attached to spindle fibers from opposite poles.
In anaphase, the sister chromatids are pulled apart toward opposite poles of the cell. This separation is facilitated by the shortening of the spindle fibers attached to the chromatids.
During prophase, the chromosomes condense and become visible, but the sister chromatids are still attached to each other at the centromere.
In telophase, the separated chromatids reach the opposite poles, and the nuclear envelope begins to reform around each set of chromosomes, marking the near end of mitosis.