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Multiple Choice
During which phase of mitosis do the sister chromatids separate?
A
Anaphase
B
Prophase
C
Telophase
D
Metaphase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that sister chromatids are identical copies of a chromosome connected by a centromere. During mitosis, these chromatids need to be separated to ensure each daughter cell receives an identical set of chromosomes.
Review the characteristics of each phase of mitosis: Prophase involves the condensation of chromatin into visible chromosomes and the formation of the mitotic spindle. Metaphase is when chromosomes align at the cell's equatorial plane. Anaphase is characterized by the separation of sister chromatids. Telophase involves the reformation of the nuclear envelope around the separated chromatids.
Focus on anaphase, where the sister chromatids are pulled apart by the spindle fibers attached to the centromeres, moving towards opposite poles of the cell. This separation is crucial for the equal distribution of genetic material.
Conclude that the phase during which sister chromatids separate is anaphase, as this is when the chromatids are split and moved to opposite ends of the cell, ensuring each new cell will have the correct number of chromosomes.