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Multiple Choice
Which of the following is the reason why infants rarely experience anaphylactic reactions?
A
They are exposed to fewer allergens due to their diet.
B
They have a higher concentration of antihistamines in their blood.
C
Their immune systems are not fully developed to produce strong IgE-mediated responses.
D
Their skin acts as a complete barrier to all allergens.
Verified step by step guidance
1
Understand the context of the question: Anaphylactic reactions are severe allergic responses mediated by the immune system, specifically involving Immunoglobulin E (IgE) antibodies. These reactions occur when the immune system overreacts to allergens.
Review the immune system development in infants: Infants have immature immune systems, meaning their ability to produce certain immune responses, including IgE-mediated responses, is not fully developed.
Analyze the role of IgE in anaphylaxis: IgE antibodies are responsible for triggering the release of histamines and other chemicals from mast cells, leading to anaphylactic symptoms. If IgE production is limited, the likelihood of anaphylaxis decreases.
Evaluate the other options: Infants are exposed to fewer allergens due to their diet, but this does not fully explain the rarity of anaphylaxis. Similarly, the idea that infants have higher concentrations of antihistamines or that their skin acts as a complete barrier is not supported by biological evidence.
Conclude that the correct reason is the underdeveloped immune system in infants, which limits their ability to produce strong IgE-mediated responses, reducing the likelihood of anaphylactic reactions.