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Multiple Choice
Which of the following describes a metabolic consequence of a shortage of oxygen in muscle cells?
A
Lactic acid accumulates due to increased fermentation.
B
ATP production by oxidative phosphorylation increases.
C
The electron transport chain operates at a higher rate.
D
Glucose is converted directly into carbon dioxide and water.
Verified step by step guidance
1
Understand the role of oxygen in cellular respiration: Oxygen is the final electron acceptor in the electron transport chain during aerobic respiration. Without sufficient oxygen, the electron transport chain cannot function effectively.
Recognize the alternative pathway: When oxygen is scarce, cells switch to anaerobic respiration or fermentation to produce ATP. This process does not rely on the electron transport chain and instead uses glycolysis followed by fermentation.
Identify the byproducts of fermentation: In muscle cells, fermentation leads to the conversion of pyruvate (produced during glycolysis) into lactic acid. This occurs because pyruvate cannot enter the mitochondria for further oxidation in the absence of oxygen.
Compare ATP production methods: Oxidative phosphorylation (aerobic respiration) produces significantly more ATP than fermentation. However, during oxygen shortage, ATP production by oxidative phosphorylation decreases, and fermentation becomes the primary source of ATP.
Eliminate incorrect options: Increased fermentation leads to lactic acid accumulation, not increased oxidative phosphorylation or electron transport chain activity. Glucose is not directly converted into carbon dioxide and water during fermentation; instead, it is converted into lactic acid.