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Multiple Choice
Which enzyme joins the gaps between synthesized DNA fragments of the lagging strand?
A
DNA ligase
B
Helicase
C
DNA polymerase
D
Primase
Verified step by step guidance
1
Understand the process of DNA replication, which involves the synthesis of a new DNA strand complementary to the template strand.
Recognize that the lagging strand is synthesized in short segments known as Okazaki fragments due to the antiparallel nature of DNA.
Identify the role of different enzymes in DNA replication: Helicase unwinds the DNA double helix, DNA polymerase synthesizes new DNA strands, and Primase synthesizes RNA primers.
Focus on the specific task of joining Okazaki fragments on the lagging strand, which involves sealing the nicks between these fragments.
Learn that DNA ligase is the enzyme responsible for joining the Okazaki fragments by forming phosphodiester bonds between the DNA fragments, thus completing the DNA strand.