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Multiple Choice
Which of the following mechanisms is responsible for monitoring a cell's DNA for mutations?
A
DNA replication
B
Translation
C
Mismatch repair
D
Transcription
Verified step by step guidance
1
Understand the context: The question is about cellular mechanisms that monitor DNA for mutations, which are changes in the DNA sequence.
Identify the process: Mismatch repair is a cellular mechanism that corrects errors introduced during DNA replication. It specifically targets mismatches that occur when incorrect nucleotides are incorporated into the newly synthesized DNA strand.
Differentiate from other processes: DNA replication is the process of copying DNA, transcription is the process of synthesizing RNA from DNA, and translation is the process of synthesizing proteins from RNA. None of these directly monitor or correct DNA mutations.
Focus on mismatch repair: During DNA replication, if a mismatch occurs, the mismatch repair system identifies and repairs these errors to maintain genetic stability.
Conclude with the role of mismatch repair: Mismatch repair is crucial for reducing the mutation rate and preventing genetic diseases by ensuring the fidelity of DNA replication.