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Multiple Choice
What is the primary function of DNA methylation in eukaryotic cells?
A
It activates gene expression by loosening chromatin structure.
B
It silences gene expression by tightening chromatin structure.
C
It repairs damaged DNA by replacing methylated bases.
D
It facilitates DNA replication by unwinding the double helix.
Verified step by step guidance
1
Understand the concept of DNA methylation: DNA methylation involves the addition of a methyl group (CH₃) to the DNA molecule, typically at cytosine bases in the context of CpG dinucleotides.
Recognize the impact of DNA methylation on gene expression: Methylation generally leads to the repression of gene expression by affecting the chromatin structure.
Explore how methylation affects chromatin: Methylation can lead to a tighter chromatin structure, making it less accessible for transcription factors and RNA polymerase, thus silencing gene expression.
Differentiate DNA methylation from other processes: DNA methylation is distinct from DNA repair mechanisms and does not directly facilitate DNA replication or activate gene expression.
Conclude the primary function: The primary function of DNA methylation in eukaryotic cells is to silence gene expression by tightening the chromatin structure, preventing transcription.