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Multiple Choice
What type of mutation involves the loss of a single nucleotide, leading to a frameshift mutation?
A
Insertion
B
Substitution
C
Deletion
D
Duplication
Verified step by step guidance
1
Understand the concept of a frameshift mutation: A frameshift mutation occurs when nucleotides are inserted or deleted from the DNA sequence, causing a shift in the reading frame of the genetic code.
Identify the types of mutations: Insertion, Substitution, Deletion, and Duplication are common types of mutations.
Define each mutation type: Insertion adds one or more nucleotides, Substitution replaces one nucleotide with another, Deletion removes one or more nucleotides, and Duplication repeats a segment of DNA.
Focus on Deletion: A deletion mutation involves the removal of a nucleotide from the DNA sequence, which can lead to a frameshift if the number of nucleotides removed is not a multiple of three.
Conclude that a deletion of a single nucleotide will cause a frameshift mutation, as it alters the triplet codon reading frame used during translation.