Multiple Choice
Sickle cell disease is caused by a missense mutation that affects which of the following proteins?
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15. Gene Expression
Mutations
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A chromosome has an inversion. Which of the following describes a pericentric inversion?
A
An inversion that results in a duplication of genetic material
B
An inversion that occurs outside the centromere
C
An inversion that includes the centromere
D
An inversion that affects only one arm of the chromosome
Verified step by step guidance1
Understand that a chromosome inversion is a type of mutation where a segment of a chromosome is reversed end to end.
Recognize that there are two main types of inversions: pericentric and paracentric.
A pericentric inversion includes the centromere within the inverted region, while a paracentric inversion does not include the centromere.
In the context of the problem, identify that the correct description of a pericentric inversion is 'An inversion that includes the centromere'.
Review the options given and match the correct description to the definition of a pericentric inversion.
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