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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

17. Mutation, Repair, and Recombination

DNA Repair

Genetics

17. Mutation, Repair, and Recombination

DNA Repair

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Multiple Choice

What is the primary role of exonucleases during DNA replication?

They synthesize new DNA strands by adding nucleotides to the template strand.

They join Okazaki fragments together on the lagging strand.

They remove incorrectly paired nucleotides from the newly synthesized DNA strand.

They unwind the DNA double helix ahead of the replication fork.

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Verified step by step guidance

Understand that DNA replication involves multiple enzymes, each with a specific role to ensure accurate copying of genetic material.

Recall that exonucleases are enzymes that remove nucleotides from the ends of DNA strands, which is crucial for proofreading during replication.

Recognize that during DNA replication, DNA polymerases can sometimes incorporate incorrect nucleotides, and exonucleases help by excising these mismatched bases.

Note that this proofreading activity of exonucleases improves the fidelity of DNA replication by removing incorrectly paired nucleotides from the newly synthesized strand.

Differentiate exonuclease activity from other enzymes: DNA polymerases synthesize DNA, ligases join Okazaki fragments, and helicases unwind the DNA helix.