Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which of the following is NOT involved in the unwinding of DNA during replication?
A
Topoisomerase
B
Single-strand binding proteins
C
Helicase
D
DNA ligase
Verified step by step guidance
1
Step 1: Understand the role of each protein listed in the context of DNA replication, specifically focusing on the unwinding process.
Step 2: Recall that Helicase is the enzyme responsible for breaking hydrogen bonds between DNA strands, effectively unwinding the double helix.
Step 3: Recognize that Single-strand binding proteins stabilize the separated DNA strands to prevent them from re-annealing during replication.
Step 4: Know that Topoisomerase relieves the torsional strain ahead of the replication fork by cutting and rejoining DNA strands, facilitating unwinding.
Step 5: Identify that DNA ligase is involved later in replication, specifically in joining Okazaki fragments on the lagging strand, and does not participate in the unwinding process.