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Multiple Choice
Which of the following base pairs would be targeted and repaired by a mismatch repair system?
A
C-G
B
T-A
C
A-T
D
G-T
Verified step by step guidance
1
Understand that the mismatch repair system targets base pairs that are incorrectly paired, meaning the bases do not follow the standard Watson-Crick base pairing rules.
Recall the normal base pairing rules: Cytosine (C) pairs with Guanine (G), and Adenine (A) pairs with Thymine (T). So, correct pairs are C-G and A-T (or T-A).
Identify that pairs like G-T do not follow these standard rules and represent mismatches that can occur during DNA replication or due to damage.
Recognize that the mismatch repair system scans the DNA for such incorrect pairs (e.g., G-T) and initiates repair to restore the correct base pairing.
Conclude that among the options given, the mismatch repair system would target the G-T pair because it is a mismatch, unlike the correctly paired C-G, T-A, or A-T.