Textbook Question
What type of enzyme regulation occurs in the following situations?
a. Buildup of the product of the pathway that converts glucose to pyruvate stops at the first enzyme in the multistep process.
19. Enzymes
Enzyme Regulation: Feedback Control
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Is the following diagram a correct illustration of feedback control?
A
Yes
B
No
Verified step by step guidance1
Identify the components of the diagram: The diagram shows a series of reactions where A is converted to F through intermediates B, C, D, and E, with each step catalyzed by enzymes E1, E2, E3, E4, and E5.
Understand feedback control: Feedback control in biochemical pathways typically involves the end product of a pathway inhibiting an earlier step, often the first enzyme, to regulate the pathway's activity.
Analyze the diagram for feedback control: In the diagram, there is an arrow from F back to the step between D and E, indicating that F might be inhibiting the enzyme E4.
Determine if the feedback is correct: For effective feedback control, the end product should inhibit an earlier step, ideally the first enzyme (E1), to prevent the entire pathway from proceeding when the product is abundant.
Conclude the analysis: Since the feedback in the diagram is not affecting the first enzyme (E1) but rather a later step (E4), this does not represent a typical feedback control mechanism, which is why the correct answer is 'No'.
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