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Multiple Choice
Which type of membrane-bound receptor requires an effector protein to initiate a signal transduction pathway?
A
G protein-coupled receptor (GPCR)
B
Ion channel receptor
C
Intracellular receptor
D
Receptor tyrosine kinase
Verified step by step guidance
1
Understand the role of membrane-bound receptors in cell signaling. These receptors are proteins located on the cell membrane that receive signals from outside the cell and initiate a response inside the cell.
Identify the types of membrane-bound receptors listed: G protein-coupled receptor (GPCR), Ion channel receptor, and Receptor tyrosine kinase. Note that intracellular receptors are not membrane-bound as they are located inside the cell.
Learn about G protein-coupled receptors (GPCRs). These receptors interact with G proteins, which are intracellular proteins that act as molecular switches. When a GPCR is activated by a ligand, it undergoes a conformational change that allows it to activate an associated G protein.
Recognize that the activation of the G protein by the GPCR leads to the activation of an effector protein. The effector protein then generates a second messenger, which propagates the signal within the cell, leading to a cellular response.
Conclude that the G protein-coupled receptor (GPCR) is the type of membrane-bound receptor that requires an effector protein to initiate a signal transduction pathway, as it relies on the G protein to activate downstream signaling components.