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Multiple Choice
What is checked during the G1 checkpoint of the cell cycle?
A
Chromosome alignment
B
Spindle fiber attachment
C
DNA damage and cell size
D
DNA replication completion
Verified step by step guidance
1
Understand the context of the cell cycle: The cell cycle is a series of phases that a cell goes through to divide and produce new cells. It includes the G1, S, G2, and M phases.
Identify the role of the G1 checkpoint: The G1 checkpoint is a critical control point where the cell assesses whether it is ready to proceed with DNA synthesis in the S phase.
Determine what is checked at the G1 checkpoint: At this checkpoint, the cell checks for DNA damage and ensures that the cell has reached an adequate size to support division.
Differentiate from other checkpoints: Unlike the G2 checkpoint, which checks for DNA replication completion, or the M checkpoint, which checks for chromosome alignment and spindle fiber attachment, the G1 checkpoint focuses on DNA integrity and cell size.
Conclude the importance of the G1 checkpoint: This checkpoint helps prevent the division of cells with damaged DNA or insufficient size, thereby maintaining genomic stability and proper cell function.