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Multiple Choice
Which of the following general mechanisms appear to be involved in the formation of cancer cells?
A
Enhanced DNA repair mechanisms
B
Stable genome with low mutation rates
C
Activation of oncogenes and inactivation of tumor suppressor genes
D
Increased apoptosis and reduced cell proliferation
Verified step by step guidance
1
Understand the context of cancer cell formation: Cancer arises due to disruptions in normal cellular processes, often involving genetic mutations and changes in regulatory mechanisms.
Review the role of oncogenes: Oncogenes are mutated or overexpressed versions of normal genes (proto-oncogenes) that promote cell growth and division. Their activation can lead to uncontrolled cell proliferation.
Examine the role of tumor suppressor genes: Tumor suppressor genes normally act to inhibit cell growth or promote apoptosis (programmed cell death). Their inactivation removes these regulatory checks, allowing cells to grow uncontrollably.
Analyze the incorrect options: Enhanced DNA repair mechanisms and stable genomes with low mutation rates would typically prevent cancer formation, not contribute to it. Increased apoptosis and reduced cell proliferation are also protective mechanisms against cancer, not causes.
Conclude that the correct mechanisms involved in cancer cell formation are the activation of oncogenes and the inactivation of tumor suppressor genes, as these directly lead to uncontrolled cell growth and survival.