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Multiple Choice
What is the primary difference between integral and peripheral membrane proteins?
A
Integral proteins can be easily removed from the membrane, while peripheral proteins cannot.
B
Integral proteins are embedded within the lipid bilayer, while peripheral proteins are attached to the surface.
C
Integral proteins are only found on the outer surface of the membrane, while peripheral proteins span the entire membrane.
D
Integral proteins are involved in cell signaling, while peripheral proteins are involved in transport.
Verified step by step guidance
1
Begin by understanding the structure of the cell membrane, which is primarily composed of a lipid bilayer. This bilayer provides a fluid matrix for proteins to be embedded or attached.
Integral membrane proteins are embedded within the lipid bilayer. They have hydrophobic regions that interact with the hydrophobic core of the lipid bilayer, allowing them to be firmly anchored within the membrane.
Peripheral membrane proteins, on the other hand, are not embedded within the lipid bilayer. Instead, they are attached to the membrane's surface, often through interactions with integral proteins or the polar heads of lipids.
Consider the functional roles of these proteins: integral proteins often play roles in transport and signaling due to their position spanning the membrane, while peripheral proteins may be involved in signaling pathways or maintaining the cell's shape.
Reflect on the ease of removal: integral proteins require disruption of the lipid bilayer to be removed, whereas peripheral proteins can be detached more easily, often by changing ionic conditions or pH.