Multiple Choice
Which of the following would occur from a mutation in the gene's promoter region?
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15. Gene Expression
Mutations
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Assume that a point mutation changes the codon AUU to AUC. Why is this considered a silent mutation?
A
The mutation occurs in a non-coding region of the DNA.
B
The mutation results in a stop codon, terminating translation.
C
Both codons code for the amino acid isoleucine.
D
The mutation changes the reading frame of the mRNA.
Verified step by step guidance1
Understand what a point mutation is: A point mutation is a change in a single nucleotide base in the DNA or RNA sequence.
Identify the original and mutated codons: The original codon is AUU, and the mutated codon is AUC.
Determine the amino acids coded by these codons: Use the genetic code chart to find that both AUU and AUC code for the amino acid isoleucine.
Define a silent mutation: A silent mutation is a change in the nucleotide sequence that does not alter the amino acid sequence of the protein.
Conclude why this is a silent mutation: Since both codons code for the same amino acid, isoleucine, the mutation does not change the protein's structure or function, making it a silent mutation.
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